UNIVERSITY OF DAR ES SALAAM
COLLEGE OF NATURAL AND APPLIED SCIENCES (CONAS)

GATAMBWA DENNIS MUKANDALA

Lecturer , College Of Natural And Applied Sciences
Education:

PhD in Biomolecular and Biomedical Sciences (Neuroscience Department) from University College Dublin (UCD)

Teaching:

Dr. Mukandala is currently involved in teaching the following courses:

  •  Vertebrate Anatomy and Physiology I
  • Vertebrate Anatomy and Physiology II
  • Cell Biology and Molecular Genetics
  • Advanced Physiology
  • Biological Methods and Techniques

Research:

Research interests:  He is very passionate in researching non-communicable diseases that affect the brain and spinal cord. There needs to be more research conducted in this area in Africa.

Projects:

  1. Parkinson’s Disease and its Social and Economic Impact in Tanzania: 2018 – 2020.
  2. Etiology of Poor Pregnancy Outcomes in HIV-1 positive Pregnant Women on Antiretroviral Therapy: 2018-2020.
  3. To assess the Epidemiology and distribution of Hydrocephalus in Children at Muhimbili National Hospital in Dar Es Salaam Region: 2017 –todate.
  4. A role for CREB but not COX-2 in the TNF-alpha-induced potentiation of LTP post hypoxia: 2017 – todate.
  5. Effect of CAG extended repeats on CUG-BP1 in cultured cells. August2003 – May 2004.
  6. Bit1 Mediates Apoptotic Function in a Phosphatase Dependent Manner:September – December 2007.  

Publications:

  1. Lanigan, S., Corcoran, A.E, Wall, A., Mukandala, G., and O'Connor, J.J. Acute hypoxic exposure and prolyl-hydroxylse inhibition improve synaptic transmission recovery time from a subsequent hypoxic insult in rat hippocampus. Brain Res. 2018; 1701: 212-218.
  2. Mukandala, G., Tynan, R., Lanigan, S., and O'Connor, J.J. The effects of hypoxia and inflammation on synaptic signaling in the CNS. Brain Sci. 2016; 6(6): 1-14.
  3. Mukandala,G 1., Wall, A.M1., Greig, N.H., and O'Connor, J.J. Tumor necrosis factor-α potentiates long-term potentiation in the rat dentate gyrus after acute hypoxia. J Neurosci Res. 2015; 93(5): 815-829.
  4. Gaultier, A1., Wu,X., LeMoan, N., Takimoto, S., Mukandala, G., Akasoglou, K., Campana,W.M., and Gonias, S.L. Low-density lipoprotein receptor-related protein1 is an essential receptor for myelin phagocytosis.  Jour. Cell Sci. 2009; 122(8): 1155-1162.
  5. Mantuano, E1., Mukandala, G., Li, X., Campana, W.M., and Gonias, S.L. Molecular Dissection of the Human Alpha2-Macroglobulin Subunit Reveals Domains with Antagonistic Activities in Cell Signaling. Jour. Bio. Chem. 2008; 283(29): 19904-19911.
  6. Krygier, E1., Lin, G., Mendes, J., Mukandala, G., Azar, D., and Jones, A. Segmental Dynamics of Head-to-Head Polypropylene and Polyisobutylene in their Blend and Pure Components. Macromolecules. 2005; 38(18): 7721-7729.